Online Directory: South Carolina, USA
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Communities designated in blue are Members of Sister Cities International. Click on a city name to learn more about its sister city initiatives.
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| Community | Website | Sister City | Website | |
| Anderson | ||||
| Charleston | Spoleto, Umbria, Italy | |||
| Clemson |  | |||
| Clover | Larne, Northern Ireland, UK | |||
| Columbia | | Chelyabinsk, Chelyabinskaya, Russia | ||
| Columbia | | Cluj Napoca, Cluj, Romania | ||
| Columbia | | Plovdiv, Plovdiv, Bulgaria | ||
| Columbia | | Kaiserslautern, Rheinland-Pfalz, Germany | ||
| Greenville | | Bergamo, Lombardia, Italy | ||
| Greenville | | Kortrijk, West-Vlaanderen, Belgium | ||
| Greenville | | Tianjin Port Free Trade Zone, Tianjin, China | ||
| Myrtle Beach | Burlington, Ontario, Canada | |||
| Myrtle Beach | Keighley, England, UK | |||
| Myrtle Beach | Pinamar, Buenos Aires, Argentina | |||
| Newberry | Hamm/Sieg, Rheinland-Pfalz, Germany | |||
| Pendleton | Western Isles, Scotland, UK | |||
| York County | | Larne, Northern Ireland, UK | ||
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